Top 10 road trips to St. Louis

Indianapolis to St. Louis
starting from Indianapolis
46 minutes → Cloverdale
39 minutes → Terre Haute
41 minutes → Casey
49 minutes → Effingham
53 minutes → Greenville
45 minutes → Collinsville
23 minutes → St. Louis
5 hours of driving
Chicago to St. Louis
starting from Chicago
1.5 hours → Dwight
1 hour → Bloomington
1 hour → Springfield
52 minutes → Carlinville
1 hour → St. Louis



5.5 hours of driving
Louisville to St. Louis
starting from Louisville
1 hour → Ferdinand
55 minutes → Evansville
44 minutes → Grayville
1 hour → Mount Vernon
36 minutes → Nashville
48 minutes → O'Fallon
22 minutes → St. Louis
5.5 hours of driving
Memphis to St. Louis
starting from Memphis
53 minutes → Keiser
1 hour → Hayti
1 hour → Sikeston
40 minutes → Cape Girardeau
45 minutes → Perryville
1 hour → Pevely
31 minutes → St. Louis
6 hours of driving
Nashville to St. Louis
starting from Nashville
53 minutes → Clarksville
40 minutes → Hopkinsville
53 minutes → Grand Rivers
1 hour → Cache River State Natural Area
1 hour → Burton's Cafe
47 minutes → Nashville
60 minutes → St. Louis
6.5 hours of driving
Little Rock to St. Louis
starting from Little Rock
1.5 hours → Mark Martin Ford
1 hour → Pocahontas
1 hour → Poplar Bluff
1.5 hours → Bonne Terre
1 hour → St. Louis



7 hours of driving
Lexington to St. Louis
starting from Lexington
1.5 hours → Louisville
1.5 hours → Jasper
1 hour → Evansville
1.5 hours → Mount Vernon
1 hour → St. Louis



7 hours of driving
Cincinnati to St. Louis
starting from Cincinnati
2 hours → Louisville
1.5 hours → Jasper
1 hour → Evansville
44 minutes → Grayville
1 hour → Mount Vernon
1 hour → St. Louis


7.5 hours of driving
Madison to St. Louis
starting from Madison
2 hours → DeKalb
1 hour → Starved Rock State Park
1.5 hours → Bloomington
1.5 hours → Oak Ridge Cemetery
1 hour → Old 66
53 minutes → St. Louis


7.5 hours of driving
Birmingham to St. Louis
starting from Birmingham
1.5 hours → Decatur
2 hours → Nashville
2 hours → Grand Rivers
1.5 hours → Burton's Cafe
1.5 hours → St. Louis



8.5 hours of driving

From:
     

To:
     


Search for St. Louis road trips and plan a quick drive in a weekend or less. Select your hometown as a starting point and explore alternate routes to find the best roads to take for your St. Louis vacation. Did you mean to start from St. Louis instead? Find routes from Leesburg (Virginia) to St. Louis and start planning your trip!