Top 10 road trips to St. Louis

Indianapolis to St. Louis
starting from Indianapolis
1.5 hours → Rosedale
56 minutes → Westfield
45 minutes → Effingham
53 minutes → Greenville
50 minutes → Shiloh
26 minutes → St. Louis


5 hours of driving
Memphis to St. Louis
starting from Memphis
1 hour → Blytheville
1 hour → Sikeston
40 minutes → Cape Girardeau
1 hour → Sainte Genevieve
42 minutes → Pevely
31 minutes → St. Louis


5.5 hours of driving
Chicago to St. Louis
starting from Chicago
1 hour → Morris
47 minutes → Pontiac
46 minutes → Bloomington
1 hour → Springfield
52 minutes → Carlinville
1 hour → St. Louis


5.5 hours of driving
Louisville to St. Louis
starting from Louisville
1.5 hours → Jasper
58 minutes → Thai Papaya Cuisine Inc
1.5 hours → McLeansboro
1 hour → Nashville
40 minutes → Shiloh
26 minutes → St. Louis


6 hours of driving
Nashville to St. Louis
starting from Nashville
53 minutes → Clarksville
40 minutes → Hopkinsville
53 minutes → Grand Rivers
59 minutes → Shawnee National Forest
1 hour → Burton's Cafe
47 minutes → Nashville
60 minutes → St. Louis
6 hours of driving
Cincinnati to St. Louis
starting from Cincinnati
1.5 hours → The Grand Buffet
44 minutes → Gray Brothers Cafeteria
1.5 hours → Terre Haute
1 hour → Effingham
1.5 hours → Old 66
53 minutes → St. Louis


7 hours of driving
Milwaukee to St. Louis
starting from Milwaukee
44 minutes → Mars Cheese Castle
1 hour → Chicago
1.5 hours → Pontiac
46 minutes → Bloomington
1 hour → Springfield
1 hour → Old 66
53 minutes → St. Louis
7.5 hours of driving
Little Rock to St. Louis
starting from Little Rock
57 minutes → Searcy
49 minutes → Mark Martin Ford
59 minutes → Weiner
1 hour → Pocahontas
1 hour → Poplar Bluff
1.5 hours → Bonne Terre
1 hour → St. Louis
8 hours of driving
Columbus to St. Louis
starting from Columbus
1 hour → Dayton
49 minutes → Richmond
1.5 hours → Indianapolis
1.5 hours → Terre Haute
1.5 hours → Altamont
1 hour → Old 66
53 minutes → St. Louis
8 hours of driving
Birmingham to St. Louis
starting from Birmingham
1.5 hours → Decatur
2 hours → Nashville
2 hours → Grand Rivers
2 hours → Burton's Cafe
1.5 hours → St. Louis



8.5 hours of driving

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Search for St. Louis road trips and plan a quick drive in a weekend or less. Select your hometown as a starting point and explore alternate routes to find the best roads to take for your St. Louis vacation. Did you mean to start from St. Louis instead? Find routes from Council Bluffs to St. Louis and start planning your trip!