Top 15 road trips from St. Louis

St. Louis to Kansas City
starting from St. Louis
56 minutes → Warrenton
1 hour → Columbia
60 minutes → Sweet Springs
1 hour → Independence
19 minutes → Kansas City



4.5 hours of driving
St. Louis to Indianapolis
starting from St. Louis
57 minutes → Greenville
53 minutes → Altamont
1 hour → Casey
49 minutes → Terre Haute
39 minutes → Cloverdale
36 minutes → Gray Brothers Cafeteria
28 minutes → Indianapolis

5.5 hours of driving
St. Louis to Memphis
starting from St. Louis
1 hour → Sainte Genevieve
1 hour → Cape Girardeau
41 minutes → Sikeston
1 hour → Hayti
1 hour → Keiser
53 minutes → Memphis


6 hours of driving
St. Louis to Louisville
starting from St. Louis
59 minutes → Nashville
1.5 hours → Grayville
44 minutes → Evansville
1 hour → Jasper
1 hour → Corydon
31 minutes → Louisville


6 hours of driving
St. Louis to Nashville
starting from St. Louis
59 minutes → Nashville
47 minutes → Burton's Cafe
1 hour → Cache River State Natural Area
42 minutes → Paducah
1.5 hours → Hopkinsville
1 hour → Nashville


6 hours of driving
St. Louis to Chicago
starting from St. Louis
53 minutes → Old 66
1 hour → Springfield
1 hour → McLean
1 hour → Pontiac
1.5 hours → Naperville
37 minutes → Chicago


6.5 hours of driving
St. Louis to Little Rock
starting from St. Louis
1 hour → Bonne Terre
1.5 hours → Poplar Bluff
1 hour → Pocahontas
1 hour → Newport
1.5 hours → Jacksonville
21 minutes → Little Rock


7 hours of driving
St. Louis to Madison
starting from St. Louis
53 minutes → Old 66
1 hour → Springfield
1 hour → Bloomington
59 minutes → Oglesby
1 hour → DeKalb
1.5 hours → Edgerton
35 minutes → Madison

7 hours of driving
St. Louis to Des Moines
starting from St. Louis
49 minutes → O'Fallon Brewery
60 minutes → Bowling Green
1 hour → Bay Bridge
1 hour → Nauvoo
1 hour → Fairfield
59 minutes → Oskaloosa
58 minutes → Colfax
27 minutes → Des Moines
7.5 hours of driving
St. Louis to Lexington
starting from St. Louis
59 minutes → Nashville
2 hours → Evansville
1 hour → Jasper
1.5 hours → Louisville
58 minutes → Frankfort
43 minutes → Lexington


7.5 hours of driving
St. Louis to Tulsa
starting from St. Louis
1.5 hours → Cuba
1 hour → Fort Leonard Wood
1.5 hours → Springfield
1.5 hours → Carthage
2 hours → Claremore
31 minutes → Tulsa


8 hours of driving
St. Louis to Chattanooga
starting from St. Louis
59 minutes → Nashville
2 hours → Paducah
1.5 hours → Hopkinsville
1 hour → Nashville
1 hour → Manchester
1 hour → Chattanooga


8 hours of driving
St. Louis to Cincinnati
starting from St. Louis
59 minutes → Nashville
1.5 hours → Grayville
44 minutes → Evansville
1 hour → Jasper
1.5 hours → Churchill Downs
1.5 hours → Dry Ridge
24 minutes → Cincinnati

8 hours of driving
St. Louis to Milwaukee
starting from St. Louis
53 minutes → Old 66
1 hour → Springfield
1 hour → McLean
1.5 hours → Starved Rock State Park
1 hour → DeKalb
44 minutes → Loves Park
1 hour → Big Bend
27 minutes → Milwaukee
8 hours of driving
St. Louis to Birmingham
starting from St. Louis
1 hour → Mount Vernon
1.5 hours → Paducah
2 hours → Nashville
2 hours → Fairfield Inn by Marriott Nashville at Opryland
2 hours → Birmingham



9 hours of driving

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Find day trips near St. Louis and explore nearby destinations that are easily drivable. Once you've picked a place, you can search for alternate routes that might have more interesting stops along the way. If you're looking for all the possible destinations, try searching for a radius of 100 miles from St. Louis up to 400 miles from St. Louis or anything in between. Did you mean to drive to St. Louis instead? Plan a longer getaway and do a road trip to Kansas from St. Louis.