Top 15 road trips from St. Louis

St. Louis to Indianapolis
starting from St. Louis
57 minutes → Greenville
46 minutes → Altamont
56 minutes → Westfield
42 minutes → Terre Haute
1.5 hours → Gray Brothers Cafeteria
28 minutes → Indianapolis


5 hours of driving
St. Louis to Memphis
starting from St. Louis
1 hour → Sainte Genevieve
49 minutes → Sedgewickville
1 hour → Sikeston
52 minutes → Hayti
1.5 hours → Turrell
30 minutes → Memphis


6 hours of driving
St. Louis to Nashville
starting from St. Louis
59 minutes → Nashville
47 minutes → Burton's Cafe
1 hour → Shawnee National Forest
44 minutes → Paducah
1.5 hours → Hopkinsville
1 hour → Nashville


6 hours of driving
St. Louis to Louisville
starting from St. Louis
59 minutes → Nashville
36 minutes → Mount Vernon
1.5 hours → Evansville
1 hour → Jasper
1 hour → Corydon
31 minutes → Louisville


6 hours of driving
St. Louis to Chicago
starting from St. Louis
53 minutes → Old 66
1 hour → Springfield
53 minutes → McLean
51 minutes → Pontiac
47 minutes → Morris
55 minutes → Naperville
37 minutes → Chicago

6 hours of driving
St. Louis to Cincinnati
starting from St. Louis
53 minutes → Old 66
1 hour → Altamont
1.5 hours → Terre Haute
1.5 hours → Indianapolis
2 hours → Creation Museum
25 minutes → Cincinnati


7 hours of driving
St. Louis to Milwaukee
starting from St. Louis
53 minutes → Old 66
1 hour → Springfield
53 minutes → McLean
51 minutes → Pontiac
1 hour → Romeoville
1.5 hours → Mars Cheese Castle
44 minutes → Milwaukee

7 hours of driving
St. Louis to Lexington
starting from St. Louis
59 minutes → Nashville
2 hours → Evansville
1 hour → Jasper
1 hour → Corydon
1.5 hours → Frankfort
43 minutes → Lexington


7.5 hours of driving
St. Louis to Little Rock
starting from St. Louis
1 hour → Bonne Terre
1.5 hours → Wappapello
1.5 hours → Pocahontas
1 hour → Weiner
59 minutes → Mark Martin Ford
49 minutes → Searcy
54 minutes → Little Rock

7.5 hours of driving
St. Louis to Chattanooga
starting from St. Louis
59 minutes → Nashville
2 hours → Paducah
1.5 hours → Clarksville
52 minutes → Nashville
1 hour → Manchester
1 hour → Chattanooga


8 hours of driving
St. Louis to Madison
starting from St. Louis
53 minutes → Old 66
1 hour → Springfield
1 hour → Bloomington
1 hour → Streator
2 hours → Rockford
1 hour → Whitewater
51 minutes → Madison

8 hours of driving
St. Louis to Columbus
starting from St. Louis
53 minutes → Old 66
1 hour → Altamont
1 hour → Casey
41 minutes → Terre Haute
1.5 hours → Indianapolis
1.5 hours → Richmond
47 minutes → Dayton
1 hour → Columbus
8.5 hours of driving
St. Louis to Omaha
starting from St. Louis
1.5 hours → Kingdom City
2 hours → Knob Noster
1.5 hours → Oklahoma Joe's BBQ & Catering
1.5 hours → Helena
1.5 hours → Rock Port
1 hour → Omaha


8.5 hours of driving
St. Louis to Birmingham
starting from St. Louis
1 hour → Mount Vernon
1.5 hours → Paducah
2 hours → Nashville
2 hours → Fairfield Inn by Marriott Nashville at Opryland
2 hours → Birmingham



9 hours of driving
St. Louis to Kansas City
starting from St. Louis
37 minutes → St. Peters
1 hour → New Haven
54 minutes → Wellsville
1 hour → Columbia
38 minutes → Pilot Grove
42 minutes → Sweet Springs
13 hours → Independence
19 minutes → Kansas City
18.5 hours of driving

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Find day trips near St. Louis and explore nearby destinations that are easily drivable. Once you've picked a place, you can search for alternate routes that might have more interesting stops along the way. If you have more time, you can explore ideas for weekend trips from St. Louis. If you're looking for all the possible destinations, try searching for a radius of 100 miles from St. Louis up to 400 miles from St. Louis or anything in between. Did you mean to drive to St. Louis instead? Plan a longer getaway and do a road trip to Alabama from St. Louis.