Explore alternate routes from
St. Louis to
Memphis, or you can get reverse directions from
Memphis to St. Louis.
Don't forget to factor in the weather. You can check the
road conditions from St. Louis to Memphis. Check out other stops like
Sikeston,
Dyersburg, or
Little Rock. Try starting your trip from
Cahokia,
Caseyville,
East Saint Louis,
Pontoon Beach,
Florissant,
Hazelwood,
Clayton (Missouri),
Granite City, or
Brentwood (Missouri). You can also change your destination to
West Memphis,
Southaven (Mississippi), or
Marion (Arkansas).