Top 7 trips from
St. Louis
to
Lexington
St. Louis to Lexington
starting from
St. Louis
→
59 minutes
→ Nashville
2 hours
→ Evansville
2 hours
→ Jasper
1 hour
→ Corydon
2.5 hours
→ Frankfort
43 minutes
→ Lexington
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7.5 hours of driving
St. Louis to Lexington via Mount Vernon
starting from
St. Louis
→
1 hour
→ Mount Vernon
2 hours
→ Jasper
1 hour
→ Corydon
2.5 hours
→ Frankfort
43 minutes
→ Lexington
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6.5 hours of driving
St. Louis to Lexington via Bowling Green
starting from
St. Louis
→
59 minutes
→ Nashville
2 hours
→ Evansville
2 hours
→ Bowling Green
2.5 hours
→ Lexington
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7.5 hours of driving
St. Louis to Lexington via Paducah
starting from
St. Louis
→
59 minutes
→ Nashville
1.5 hours
→ Paducah
2.5 hours
→ Falls of Rough
56 minutes
→ Elizabethtown
1.5 hours
→ Lexington
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8 hours of driving
St. Louis to Lexington via Indianapolis
starting from
St. Louis
→
53 minutes
→ Old 66
1 hour
→ Altamont
48 minutes
→ Mattoon
2.5 hours
→ Indianapolis
2.5 hours
→ Frankfort
43 minutes
→ Lexington
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8.5 hours of driving
St. Louis to Lexington via Clarksville
starting from
St. Louis
→
1 hour
→ Mount Vernon
1.5 hours
→ Paducah
1.5 hours
→ Clarksville
2 hours
→ Mammoth Cave National Park
1 hour
→ Bardstown
1 hour
→ Lexington
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8.5 hours of driving
St. Louis to Lexington via Nashville
starting from
St. Louis
→
1 hour
→ Mount Vernon
1.5 hours
→ Cache River State Natural Area
3 hours
→ Nashville
1 hour
→ Bardstown
1 hour
→ Lexington
view full itinerary
9 hours of driving
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Explore alternate routes from
St. Louis
to
Lexington
, or you can get reverse directions from
Lexington to St. Louis
. Don't forget to factor in the weather. You can check the
road conditions from St. Louis to Lexington
. Check out other stops like
Mount Vernon (Illinois)
,
Bowling Green (Kentucky)
,
Paducah
,
Indianapolis
,
Clarksville
, or
Nashville
.