Top 9 trips from St. Louis to Key West

St. Louis to Key West via Fort Lauderdale
starting from St. Louis
3 hours → Grand Rivers
2 hours → Nashville
2 hours → Chattanooga
4 hours → Atlanta
3.5 hours → Valdosta
3.5 hours → Orlando
3 hours → Fort Lauderdale
3.5 hours → Key West
22.5 hours of driving
St. Louis to Key West via Cape Canaveral
starting from St. Louis
3 hours → Grand Rivers
2 hours → Nashville
4 hours → Atlanta
3.5 hours → Valdosta
4 hours → Cape Canaveral
3.5 hours → Miami
3.5 hours → Key West

22.5 hours of driving
St. Louis to Key West via Memphis
starting from St. Louis
4.5 hours → Memphis
3.5 hours → Birmingham
4 hours → Atlanta
3.5 hours → Valdosta
2 hours → Ocala
3.5 hours → Miami
3.5 hours → Key West

23 hours of driving
St. Louis to Key West via Jacksonville
starting from St. Louis
3 hours → Grand Rivers
2 hours → Nashville
2 hours → Chattanooga
4 hours → Atlanta
2 hours → Jacksonville
3 hours → Cape Canaveral
3.5 hours → Miami
3.5 hours → Key West
24 hours of driving
St. Louis to Key West via Savannah
starting from St. Louis
3 hours → Paducah
2 hours → Nashville
4 hours → Atlanta
4 hours → Savannah
2 hours → Jacksonville
3 hours → Cape Canaveral
3.5 hours → Miami
3.5 hours → Key West
24.5 hours of driving
St. Louis to Key West via Tallahassee
starting from St. Louis
3 hours → Grand Rivers
2 hours → Nashville
3.5 hours → Birmingham
3 hours → Tallahassee
2 hours → Jacksonville
3.5 hours → Orlando
3.5 hours → Miami
3.5 hours → Key West
24.5 hours of driving
St. Louis to Key West via Arkansas
starting from St. Louis
5.5 hours → Arkansas
4 hours → Tupelo
4 hours → Atlanta
3.5 hours → Valdosta
3.5 hours → Orlando
3.5 hours → Miami
3.5 hours → Key West

27 hours of driving
St. Louis to Key West via New Orleans
starting from St. Louis
4.5 hours → Memphis
6 hours → New Orleans
3 hours → Pensacola
3 hours → Tallahassee
3.5 hours → Orlando
3.5 hours → Miami
3.5 hours → Key West

27 hours of driving
St. Louis to Key West via Myrtle Beach
starting from St. Louis
3 hours → Paducah
2 hours → Nashville
4.5 hours → Asheville
5 hours → Myrtle Beach
4 hours → Savannah
3.5 hours → Orlando
3.5 hours → Miami
3.5 hours → Key West
29.5 hours of driving

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Explore alternate routes from St. Louis to Key West, or you can get reverse directions from Key West to St. Louis. Don't forget to factor in the weather. You can check the road conditions from St. Louis to Key West. Check out other stops like Fort Lauderdale, Cape Canaveral, Memphis, Jacksonville, Savannah, Tallahassee, Arkansas, New Orleans, or Myrtle Beach.