Explore alternate routes from
Louisville to
St. Louis, or you can get reverse directions from
St. Louis to Louisville.
Don't forget to factor in the weather. You can check the
road conditions from Louisville to St. Louis. Check out other stops like
Eddyville,
Metropolis, or
Terre Haute (Indiana). Try starting your trip from
New Albany (Indiana),
Sellersburg (Indiana),
Jeffersontown,
Jeffersonville (Indiana),
Clarksville (Indiana),
Hillview,
Georgetown (Indiana),
Prospect, or
Prairie Village (Kentucky). You can also change your destination to
Cahokia,
Caseyville,
East Saint Louis,
Pontoon Beach,
Florissant,
Hazelwood,
Clayton (Missouri),
Granite City, or
Brentwood (Missouri).