Top 6 trips from Little Rock to St. Louis

Little Rock to St. Louis
starting from Little Rock
21 minutes → Jacksonville
1 hour → Newport
1 hour → Pocahontas
1 hour → Poplar Bluff
1.5 hours → Bonne Terre
1 hour → St. Louis
6.5 hours of driving
Little Rock to St. Louis via Willow Springs
starting from Little Rock
21 minutes → Jacksonville
1.5 hours → Batesville
2 hours → Willow Springs
3 hours → St. Louis


7 hours of driving
Little Rock to St. Louis via Willow Springs
starting from Little Rock
1.5 hours → Batesville
2 hours → Willow Springs
2.5 hours → Six Flags St. Louis
42 minutes → St. Louis


7 hours of driving
Little Rock to St. Louis via Memphis
starting from Little Rock
1.5 hours → Memphis
2 hours → Sikeston
1 hour → Sainte Genevieve
1 hour → St. Louis


7 hours of driving
Little Rock to St. Louis via Harrison
starting from Little Rock
2.5 hours → Harrison
3 hours → Rolla
1.5 hours → St. Louis



7 hours of driving
Little Rock to St. Louis via Memphis
starting from Little Rock
30 minutes → Lonoke
1.5 hours → Memphis
2.5 hours → Cape Girardeau
1 hour → Sainte Genevieve
1 hour → St. Louis

7 hours of driving

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Explore alternate routes from Little Rock to St. Louis, or you can get reverse directions from St. Louis to Little Rock. Don't forget to factor in the weather. You can check the road conditions from Little Rock to St. Louis. Check out other stops like Willow Springs, Memphis, or Harrison (Arkansas). Try starting your trip from Bryant, Maumelle, North Little Rock, Jacksonville (Arkansas), Sherwood (Arkansas), Pinnacle (Arkansas), or Alexander (Arkansas). You can also change your destination to Cahokia, Caseyville, East Saint Louis, Edwardsville, Fairview Heights, Pontoon Beach, Clayton (Missouri), Granite City, or Brentwood (Missouri).