Top 6 trips from Des Moines to Sioux Falls

Des Moines to Sioux Falls
starting from Des Moines
41 minutes → Winterset
1.5 hours → Elk Horn
1 hour → Glenn Cunningham Lake
1 hour → Onawa
40 minutes → Sioux City
51 minutes → Beresford
48 minutes → Sioux Falls




6.5 hours of driving
Pleasant Hill to Sioux Falls
starting from Pleasant Hill
56 minutes → Adair
1.5 hours → Beercade
1 hour → Onawa
40 minutes → Sioux City
51 minutes → Beresford
48 minutes → Sioux Falls





6 hours of driving
Des Moines to Sioux Falls via Rushmore
starting from Des Moines
3.5 hours → Rushmore
15 minutes → Adrian
24 minutes → Luverne
29 minutes → Brandon
15 minutes → Sioux Falls KOA Journey
10 minutes → Sioux Falls




5 hours of driving
Des Moines to Sioux Falls via Dakota City
starting from Des Moines
3 hours → Dakota City
16 minutes → North Sioux City
47 minutes → Union Grove State Park
22 minutes → Beresford
26 minutes → Countryside Campground & Motel
19 minutes → Red Barn RV Park
15 minutes → Sioux Falls



5.5 hours of driving
Des Moines to Sioux Falls via Okoboji
starting from Des Moines
38 minutes → Ames
47 minutes → Webster City
1 hour → West Bend
51 minutes → Estherville
31 minutes → Okoboji
42 minutes → Worthington
45 minutes → Blue Mounds State Park
44 minutes → Falls Park
5 minutes → Sioux Falls

6 hours of driving
Des Moines to Sioux Falls via Missouri Valley
starting from Des Moines
56 minutes → Adair
36 minutes → Elk Horn
1 hour → Beercade
31 minutes → Missouri Valley
49 minutes → Onawa
40 minutes → Sioux City
44 minutes → Vermillion
34 minutes → Beresford
42 minutes → McNally's Irish Pub
9 minutes → Sioux Falls
7 hours of driving

From:
     

To:
     


Explore alternate routes from Des Moines to Sioux Falls, or you can get reverse directions from Sioux Falls to Des Moines. Don't forget to factor in the weather. You can check the road conditions from Des Moines to Sioux Falls. Check out other stops like Okoboji, Rushmore, Worthington (Minnesota), Sioux City, Estherville, Missouri Valley, Dakota City (Nebraska), Ida Grove, Templeton (Iowa), or Linn Grove. Try starting your trip from Pleasant Hill (Iowa).