Top 8 trips from Charleston to Greenville

Charleston to Greenville
starting from Charleston
5 minutes → Husk
36 minutes → Summerville
48 minutes → Santee
59 minutes → Columbia
47 minutes → Newberry
1 hour → Greenville






4.5 hours of driving
Mount Pleasant to Greenville
starting from Mount Pleasant
32 minutes → Summerville
48 minutes → Santee
47 minutes → Congaree National Park
1 hour → Newberry
1.5 hours → Coffee Underground
9 minutes → Greenville






5 hours of driving
Charleston to Greenville via Hampton
starting from Charleston
1.5 hours → Hampton
3 hours → Greenville









4.5 hours of driving
Charleston to Greenville via Columbia
starting from Charleston
32 minutes → Summerville
48 minutes → Santee
47 minutes → Congaree National Park
28 minutes → Columbia
17 minutes → Irmo
42 minutes → Newberry
34 minutes → Clinton
40 minutes → Heritage Park Amphitheatre
19 minutes → Greenville


5 hours of driving
Charleston to Greenville via Bishopville
starting from Charleston
32 minutes → Summerville
60 minutes → Manning
36 minutes → Sumter
30 minutes → Bishopville
2.5 hours → Greenville






5.5 hours of driving
Mount Pleasant to Greenville via Moncks Corner
starting from Mount Pleasant
13 minutes → Friends of the Hunley
15 minutes → Holiday Inn Express & Suites North Charleston
8 minutes → Goose Creek
25 minutes → Moncks Corner
51 minutes → Santee
59 minutes → Columbia
47 minutes → Newberry
59 minutes → Spartanburg
38 minutes → Greenville


5.5 hours of driving
Mount Pleasant to Greenville via Augusta
starting from Mount Pleasant
1 hour → Santee
1.5 hours → Aiken
28 minutes → Augusta
1 hour → Greenwood
1 hour → Coffee Underground
9 minutes → Greenville





5.5 hours of driving
Charleston to Greenville via Orangeburg
starting from Charleston
15 minutes → EVO Pizzeria
21 minutes → Ladson
12 minutes → Summerville
29 minutes → Beidler Forest
22 minutes → Peach Tree Inn
34 minutes → Orangeburg
36 minutes → Congaree National Park
1 hour → Newberry
1 hour → Heritage Park Amphitheatre
35 minutes → Spartanburg
38 minutes → Greenville
6.5 hours of driving

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Explore alternate routes from Charleston to Greenville, or you can get reverse directions from Greenville to Charleston. Don't forget to factor in the weather. You can check the road conditions from Charleston to Greenville. Check out other stops like Columbia, Augusta, Summerville, Hampton (South Carolina), Bishopville, Orangeburg, Santee (South Carolina), Moncks Corner, Elgin (South Carolina), Estill, or Columbia. Try starting your trip from Sullivan's Island or Mount Pleasant (South Carolina). You can also change your destination to Mauldin.